Choosing an appropriate glomerular filtration rate estimating equation: role of body mass index

Is Body Surface Area the Appropriate Index for Glomerular Filtration Rate?

Indexing glomerular filtration rate (GFR) for body surface area (BSA) is routine practice, but criticism has been raised on indexing GFR for BSA in children, obese and anorectic patients. Over the years other ways of indexing GFR have been proposed, including height, lean body mass, body weight, ideal weight, plasma volume, total body water and especially extracellular volume (ECV). Based on a ...

Estimating Glomerular Filtration Rate in Older People

We aimed at reviewing age-related changes in kidney structure and function, methods for estimating kidney function, and impact of reduced kidney function on geriatric outcomes, as well as the reliability and applicability of equations for estimating glomerular filtration rate (eGFR) in older patients. CKD is associated with different comorbidities and adverse outcomes such as disability and pre...

Evaluation of Glomerular Filtration Rate Estimating Formulas in Diabetic Patients with Chronic Kidney Disease

Objective: Measurement of glomerular filtration rate (GFR) is the best determinant in assessment of kidney function for diagnostic and therapeutic purposes. As extremely accurate methods of GFR measurement (i.e. Inulin clearance) are expensive and Time-consuming and due to limitations of the 24 hour urine collection method, some formula have been developed for the GFR measurement. Here we have ...

Validation of glomerular filtration rate-estimating equations in Chinese children

BACKGROUND Glomerular filtration rate (GFR) is essential for renal function evaluation and classification of chronic kidney disease (CKD), while the reference method in children are cumbersome. In the Chinese children, there was no data about GFR measured through plasma or renal clearance of the exogenous markers, and therefore no validated GFR-estimating tools in this population. METHODS We ...

estimating glomerular filtration rate in overweight and obese malaysian subjects